主观性耳鸣患者听性脑干反应特征分析

于澜; 兰兰; 冀飞; 谢林怡; 熊芬; 王秋菊

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主观性耳鸣患者听性脑干反应特征分析

临床听力检测技术专题 | 更新时间：2026-10-28

- 主观性耳鸣患者听性脑干反应特征分析
- The Characteristics Analysis of Auditory Brainstem Response for Patients with Subjective Tinnitus
- 中国听力语言康复科学杂志 2022年20卷第3期页码：174-176+179
- 作者机构：
  
  解放军总医院耳鼻咽喉头颈外科医学部国家耳鼻咽喉疾病临床医学研究中心
- 作者简介：
- 基金信息：
  
  国家自然科学重点基金项目（81830028）;国家自然科学基金青年项目（81900951,81900950）;国家自然科学基金面上项目（82171130）;军队医学科技青年培育计划孵化项目(19QNP058,21QNPY100）;军队后勤科研计生专项（19JSZ14）;北京市自然科学基金青年项目（7204312）;国家重点研发计划“主动健康和老龄化科技应对”重点专项（2020YEC2005200&2020YFC2005201）;解放军总医院医疗大数据分析及应用研究（2019MBD-005）
- DOI：
  中图分类号： R764.45
- 纸质出版：2022
- 稿件说明：
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于澜, 兰兰, 冀飞, 等. 主观性耳鸣患者听性脑干反应特征分析[J]. 中国听力语言康复科学杂志, 2022,20(3):174-176+179.

于澜, 兰兰, 冀飞, et al. The Characteristics Analysis of Auditory Brainstem Response for Patients with Subjective Tinnitus[J]. 2022, 20(3): 174-176+179.
于澜, 兰兰, 冀飞, 等. 主观性耳鸣患者听性脑干反应特征分析[J]. 中国听力语言康复科学杂志, 2022,20(3):174-176+179. DOI：

于澜, 兰兰, 冀飞, et al. The Characteristics Analysis of Auditory Brainstem Response for Patients with Subjective Tinnitus[J]. 2022, 20(3): 174-176+179. DOI：

摘要

目的探究纯音听阈正常的主观性耳鸣患者听性脑干反应（ABR）波形特征。方法选取听力正常的主观性耳鸣患者26耳作为耳鸣组（A组），年龄18～40岁，男女比例1:1，耳鸣类型均为单一频率的持续性耳鸣。选取与耳鸣组年龄、性别相匹配的听力正常受试者18耳作为对照组（B组）。耳鸣组和对照组均在符合国家标准的隔声室行纯音测听和声导抗检查，在屏蔽室行听性脑干反应测试并记录各波的潜伏期及幅值。耳鸣组行耳鸣评估。结果听性脑干反应测试结果显示，耳鸣组和对照组Ⅰ、Ⅲ、Ⅴ波的潜伏期、波间期、波幅及Ⅴ/Ⅰ波幅比均无显著差异（P>0.05）。耳鸣组波Ⅲ波幅大于波Ⅴ的比例为53.9%(14/26)，对照组则未观察到类似情况。结论对听力正常的主观性耳鸣患者行听性脑干反应检查有助于发现和随访其听觉通路的隐性功能改变。听性脑干反应的波形特征可能是某种亚型耳鸣患者的听力学特征表现。听性脑干反应幅值可能成为耳鸣诊断的一项较为客观的评估方法，对疗效判断提供参考依据。

Abstract

Objective To explore the characteristics of auditory brainstem response waveforms of subjective tinnitus patients with normal pure tone hearing thresholds. Methods 26 ears with tinnitus and normal hearing were selected as the group of tinnitus（group A）

aged 18-40 years old. The type of tinnitus was persistent tinnitus with high pitch. A total of 18 ears without tinnitus were selected with matched age and sex as the control group（group B）. Pure tone audiometry and tympanometry were performed in the sound isolation room in accordance with national standards. The latency and amplitude of auditory brainstem response of each wave were recorded in the shielded chamber. Tinnitus group underwent tinnitus assessment. Results The results of auditory brainstem response test showed that there were no significant differences between the tinnitus group and the control group in the latency

interwave period

amplitude of wave I

III

V and the amplitude ratio of wave V/I（P>0.05）. In the tinnitus group

the ratio of the wave III amplitude was larger than that of the wave V amplitude

that was 53.9%（14/26）. This condition was not observed in the control group. Conclusion The examination of auditory brainstem response in subjective tinnitus patients with normal hearing is helpful to detect and follow up the hidden functional changes of auditory pathways. The waveform characteristics of auditory brainstem response may be the manifestation of audiologic features of certain subtypes of tinnitus patients. The amplitude of auditory brainstem response may be a more objective evaluation method for the diagnosis of tinnitus

and also help to provide reference for the judgment of efficacy.

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references

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