浙江诺尔康电子科技股份有限公司/全省智能康复与神经电子转化重点实验室 杭州 310000
谭治平,E-mail: tanzp@nurotron.com
收稿:2025-12-25,
网络首发:2026-03-17,
纸质出版:2026-03-15
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谭治平,罗川,高珊仙等.听觉脑干植入技术研发进展与应用前景[J].中国听力语言康复科学杂志,2026,24(02):219-224.
TAN Zhi-ping,LUO Chuan,GAO Shan-xian,et al.Research Progress and Application Prospects of Auditory Brainstem Implantation Technology[J].Chinese Scientific Journal of Hearing and Speech Rehabilitation,2026,24(02):219-224.
谭治平,罗川,高珊仙等.听觉脑干植入技术研发进展与应用前景[J].中国听力语言康复科学杂志,2026,24(02):219-224. DOI: 10.3969/j.issn.1672-4933.2026.02.021.
TAN Zhi-ping,LUO Chuan,GAO Shan-xian,et al.Research Progress and Application Prospects of Auditory Brainstem Implantation Technology[J].Chinese Scientific Journal of Hearing and Speech Rehabilitation,2026,24(02):219-224. DOI: 10.3969/j.issn.1672-4933.2026.02.021.
听觉脑干植入(auditory brainstem implant, ABI)是针对听神经重度损伤人群的关键听觉重建技术,历经基础探索、技术优化与临床拓展3个发展阶段,已成为极重度听力损失患者,尤其是人工耳蜗植入无效者的主要康复方案。本文系统梳理了全球ABI技术的发展脉络,全面对比了Med-EL、科利耳和我国诺尔康等主流品牌的技术特征与临床定位,重点剖析了国产ABI系统的创新突破与临床价值。结合国内外临床数据,探讨了当前ABI技术面临的核心挑战,并从多模态技术融合、个性化精准诊疗、国产化生态完善等维度展望未来发展方向,旨在为ABI技术的临床推广与科研攻关提供参考。
Auditory Brainstem Implant (ABI) is a pivotal auditory restoration technology tailored for patients with severe auditory nerve lesions. Having undergone three developmental phases
basic exploration
technological optimization
and clinical expansion
it has evolved into a critical rehabilitation solution for individuals with profound hearing loss
especially those who do not benefit from cochlear implantation. This paper systematically reviews the development trajectory of global ABI technology
comprehensively compares the technical characteristics and clinical positioning of mainstream products from manufacturers
including Med-EL
Cochlear
and China's Nurotron
with a focus on analyzing the innovative breakthroughs and clinical value of domestic ABI systems. Integrating clinical data from both domestic and international sources
the paper further discusses the core challenges confronting current ABI technology and envisions future development directions from the perspectives of multimodal technology integration
personalized precision diagnosis and treatment
and improvement of localized industrial ecology
aiming to provide a vital reference for the clinical promotion and scientific research of ABI technology.
Edgerton BJ , House WF , Hitselberger W . Hearing by cochlear nucleus stimulation in humans [J ] . Ann Otol Rhinol Laryngol Suppl , 1982 , 91 ( 2 Pt 3 ): 117 - 124 .
Colletti V , Shannon RV . Auditory brainstem implants: past, present, and future [J ] . Trends Amplif , 2005 , 9 ( 3 ): 127 - 154 .
Noij KS , Kozin ED , Sethi R , et al . Systematic Review of Nontumor Pediatric Auditory Brainstem Implant Outcomes [J ] . Otolaryngol Head Neck Surg , 2015 , 153 ( 3 ): 417 - 424 .
王正敏 , 吴皓 . 听觉医学 [M ] . 上海 : 上海科学技术出版社 , 2010 . 321 - 335 .
Colletti L . Beneficial auditory and cognitive effects of auditory brainstem implantation in children [J ] . Acta Oto-Laryngologica , 2007 , 127 ( 9 ): 943 - 946 .
Shannon RV . Auditory implant research at the House Ear Institute 1989-2013 [J ] . Hearing Research , 2015 , 322 : 57 - 66 .
Sennaroglu L , Colletti V , Manrique M . Auditory brainstem implantation in children and non-Neurofibromatosis Type 2 patients: a consensus statement [J ] . Otol Neurotol , 2011 , 32 ( 2 ): 187 - 191 .
Lenarz T , Lesinski-Schiedat A , Kiefer J , et al . Speech perception with auditory brainstem implants [J ] . Cochlear Implants Int , 2015 , 16 ( Suppl 1 ): S28 - S35 .
Trouillet A , Revol E , Coen FV , et al . High-resolution prosthetic hearing with a soft auditory brainstem implant in macaques [J ] . Nat. Biomed. Eng , 2025 , 9 : 1403 - 1417 .
Veronese S , Cambiaghi M , Tommasi N , et al . Ten-year follow-up of auditory brainstem implants: From intra-operative electrical auditory brainstem responses to perceptual results [J ] . PLoS One , 2023 , 18 ( 3 ): e0282261 .
陈兵 , 戴朴 . 个性化人工听觉植入装置的研发进展 [J ] . 中华耳科学杂志 , 2023 , 21 ( 2 ): 256 - 261 .
Colletti V , Carner M , Colletti L , et al . Auditory brainstem implants in children [J ] . Acta Otolaryngol , 2011 , 131 ( 1 ): 102 - 108 .
Yu Zhang , Yongchuan Chai , Yiwen Zhang , et al . Neural Plasticity and Hearing-speech Development in Children with Auditory Brainstem Implants for Congenital Hearing Loss Due to Severe Inner Ear Malformation [J ] . Advanced Science , 2025 , 12 ( 29 ): 1 - 11 .
陶勇 , 李路明 . 脑机接口技术在听觉康复中的应用 [J ] . 中国科学:生命科学 , 2022 , 52 ( 5 ): 701 - 715 .
韩东一 . 交叉学科推动听觉植入技术创新 [J ] . 中华耳鼻咽喉头颈外科杂志 , 2023 , 58 ( 1 ): 3 - 5 .
Shannon RV , Colletti V . Information transmission with auditory brainstem implants [J ] . Hear Res , 2019 , 378 : 107768 .
Colletti V , Mondini S , Colletti L . Long-term Auditory Outcomes in Children with Auditory Brainstem Implants [J ] . Cochlear Implants International , 2018 , 19 ( 3 ): 189 - 196 .
Colletti L , Shannon RV , Colletti V . The Development of Auditory Perception in Children after Auditory Brainstem Implantation [J ] . Acta Oto-Laryngologica , 2010 , 130 ( 5 ): 567 - 573 .
Colletti L , Zoccante L . Nonverbal cognitive abilities and auditory performance in children fitted with auditory brainstem implants: preliminary report [J ] . Laryngoscope , 2008 , 118 ( 8 ): 1443 - 1448 .
Roland JT , Lee DJ , Colletti L , et al . Current status of pediatric auditory brainstem implantation in inner ear malformations; consensus statement of the Third International Pediatric ABI Meeting [J ] . Cochlear Implants International , 2024 , 25 ( sup1 ): S1 - S26 .
吴皓 , 张天宇 . 儿童听觉脑干植入的手术要点 [J ] . 中华小儿外科杂志 , 2021 , 42 ( 8 ): 701 - 705 .
韩东一 , 杨仕明 . 听觉植入技术的发展与未来 [J ] . 中国听力语言康复科学杂志 , 2020 , 18 ( 1 ): 1 - 5 .
刘博 , 孙喜斌 . 儿童听觉植入的康复策略 [J ] . 中国听力语言康复科学杂志 , 2019 , 17 ( 2 ): 81 - 84 .
周静 , 黄昭鸣 . 虚拟现实技术在听觉康复中的应用 [J ] . 中国听力语言康复科学杂志 , 2021 , 19 ( 4 ): 289 - 292 .
孙喜斌 , 梁巍 . 中国听力残疾儿童康复现状 [J ] . 中国听力语言康复科学杂志 , 2020 , 18 ( 2 ): 81 - 84 .
Kullar PJ , Freeman S , Rutherford S , et al . Paediatric auditory brainstem implant: How we do it [J ] . Acta Neurochir (Wien) , 2026 , 168 ( 1 ): 16 .
Behr R , Schwager K , Hofmann E . Auditory Brainstem Implants-Hearing Restoration in Congenitally Deaf Children [J ] . Dtsch Arztebl Int , 2022 , 119 ( 9 ): 135 - 141 .
Martins QP , Gindri BFS , Valim CD , et al . Hearing and language development in children with brainstem implants: a systematic review [J ] . Braz J Otorhinolaryngol , 2022 ,88 Suppl 3 (Suppl 3): S225 - S234 .
Deep NL , Choudhury B , Jr Roland JT . Auditory Brainstem Implantation: An Overview [J ] . J Neurol Surg B Skull Base , 2019 , 80 ( 2 ): 203 - 208 .
Wong K , Kozin ED , Kanumuri VV , et al . Auditory Brainstem Implants: Recent Progress and Future Perspectives [J ] . Front Neurosci , 2019 , 13 : 10 .
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