基于听觉电生理诱发电位的人工耳蜗植入全流程整合框架：评估、监测与优化

聂帅; 张娟

doi:10.3969/j.issn.1672-4933.2026.01.010

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基于听觉电生理诱发电位的人工耳蜗植入全流程整合框架：评估、监测与优化

听觉电生理诱发电位在人工耳蜗植入中的应用 | 更新时间：2026-07-30

- 基于听觉电生理诱发电位的人工耳蜗植入全流程整合框架：评估、监测与优化
- An Integrated Framework of Cochlear Implantation Guided by Auditory Evoked Potentials: Evaluation, Monitoring, and Optimization
- 中国听力语言康复科学杂志 2026年24卷第1期页码：51-55
- 作者机构：
  
  首都医科大学附属北京朝阳医院耳鼻咽喉头颈外科北京 100012
- 作者简介：
  
  聂帅博士住院医师；研究方向：声源定位和中枢听觉研究
  张娟，E-mail：chinayudian@sina.com
- 基金信息：
  
  国家重点研发计划(2024YFC2511101);北京市医院管理中心“扬帆”计划临床技术创新项目(ZLRK202307)
- DOI：10.3969/j.issn.1672-4933.2026.01.010
  中图分类号： R764.04
- 收稿：2025-08-31，
  
  网络首发：2026-01-09，
  
  纸质出版：2026-01-15
- 稿件说明：
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聂帅,张娟.基于听觉电生理诱发电位的人工耳蜗植入全流程整合框架：评估、监测与优化[J].中国听力语言康复科学杂志,2026,24(01):51-55.

NIE Shuai,ZHANG Juan.An Integrated Framework of Cochlear Implantation Guided by Auditory Evoked Potentials: Evaluation, Monitoring, and Optimization[J].Chinese Scientific Journal of Hearing and Speech Rehabilitation,2026,24(01):51-55.
聂帅,张娟.基于听觉电生理诱发电位的人工耳蜗植入全流程整合框架：评估、监测与优化[J].中国听力语言康复科学杂志,2026,24(01):51-55. DOI： 10.3969/j.issn.1672-4933.2026.01.010.

NIE Shuai,ZHANG Juan.An Integrated Framework of Cochlear Implantation Guided by Auditory Evoked Potentials: Evaluation, Monitoring, and Optimization[J].Chinese Scientific Journal of Hearing and Speech Rehabilitation,2026,24(01):51-55. DOI： 10.3969/j.issn.1672-4933.2026.01.010.

摘要

人工耳蜗植入是目前治疗重度至极重度感音神经性聋的主要手段。听觉电生理诱发电位（auditory evoked potentials，AEPs）作为客观、可量化的神经功能评估工具，贯穿于人工耳蜗植入的术前筛查、术中监测及术后疗效评估全过程。本文系统综述了电诱发听性脑干反应、电诱发听神经复合动作电位、耳蜗电图、电诱发中潜伏期反应以及皮层听觉诱发电位在人工耳蜗全流程管理中的应用进展。通过整合临床研究与动物模型证据，阐明了各类AEPs在听神经功能判定、术中保护、神经可塑性追踪与康复预测中的关键作用。AEPs已从传统的诊断手段发展为贯穿人工耳蜗术前评估至术后参数调试与长期管理的核心神经电生理平台，为精准听觉康复与智能化程控提供了坚实的生物学基础。

Abstract

Cochlear implantation has become the most effective intervention for severe to profound sensorineural hearing loss. Auditory evoked potentials (AEPs)

as objective and quantitative electrophysiological biomarkers

play an essential role throughout the entire cochlear implantation process—from preoperative evaluation and intraoperative monitoring to postoperative outcome prediction. This review summarizes the latest progress of major AEPs techniques

including electrical evoked auditory brainstem response (EABR)

electrical evoked compound action potential (ECAP)

electrocochleography (ECochG)

electrical evoked middle latency response (EMLR)

and cortical auditory evoked potential (CAEP). Discussing evidence from both clinical and animal studies

we highlight their distinct roles in auditory nerve integrity assessment

intraoperative safety control

neural plasticity tracking

and rehabilitation prognosis. AEPs have evolved from diagnostic tools into a core neurophysiological platform spanning preoperative assessment for cochlear implantation through postoperative parameter tuning and long-term management

providing a robust biological foundation for precision auditory rehabilitation and intelligent programming.

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references

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