卒中后基底节失语临床特征及影响因素分析

吴敏; 李泉; 徐娜

doi:10.3969/j.issn.1672-4933.2025.03.010

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卒中后基底节失语临床特征及影响因素分析

临床研究 | 更新时间：2025-05-12

- 卒中后基底节失语临床特征及影响因素分析
- Analysis of Clinical Features and Influencing Factors of Basal Ganglia Aphasia after Stroke
- 中国听力语言康复科学杂志 2025年23卷第3期页码：264-268
- 作者机构：
  
  宿迁市第一人民医院宿迁 223800
- 作者简介：
  
  吴敏本科主管护师；研究方向：危重症护理、神经相关疾病护理
  徐娜，E-mail：lujiaosi3975@163.com
- 基金信息：
- DOI：10.3969/j.issn.1672-4933.2025.03.010
  中图分类号： G762
- 收稿日期：2025-01-03，
  
  纸质出版日期：2025-05-15
- 稿件说明：
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吴敏,李泉,徐娜.卒中后基底节失语临床特征及影响因素分析[J].中国听力语言康复科学杂志,2025,23(03):264-268.

WU Min,LI Quan,XU Na.Analysis of Clinical Features and Influencing Factors of Basal Ganglia Aphasia after Stroke[J].Chinese Scientific Journal of Hearing and Speech Rehabilitation,2025,23(03):264-268.
吴敏,李泉,徐娜.卒中后基底节失语临床特征及影响因素分析[J].中国听力语言康复科学杂志,2025,23(03):264-268. DOI： 10.3969/j.issn.1672-4933.2025.03.010.

WU Min,LI Quan,XU Na.Analysis of Clinical Features and Influencing Factors of Basal Ganglia Aphasia after Stroke[J].Chinese Scientific Journal of Hearing and Speech Rehabilitation,2025,23(03):264-268. DOI： 10.3969/j.issn.1672-4933.2025.03.010.

摘要

目的

分析卒中后基底节失语的临床特征及影响因素。

方法

选取宿迁市第一人民医院2022年8月～2024年5月收治的120例基底节性脑卒中患者为研究对象，根据卒中后是否发生失语症分为失语组（32例）、言语正常组（88例）。收集两组患者临床一般资料、实验室检查指标等数据，并进行临床语言量表与神经心理学量表评估。分析卒中后基底节失语的临床特征，并应用多因素Logistic回归分析卒中后基底节失语的影响因素。

结果

失语组年龄、病变部位与言语正常组对比差异显著（

＜0.05）。失语组汉语失语成套测验（aphasia battery of Chinese，ABC）中流利性、阅读、命名、听理解、失语商（aphasia quotient，AQ）及蒙特利尔认知评估量表（Montreal cognitive assessment，MoCA）、简易精神状态量表（mini-mentalstate examination，MMSE）评分均比言语正常组低（

＜0.05），失语组患者健康问卷（patient health questionnaire，PHQ-9）、汉密尔顿抑郁量表17项（Hamilton depression scale-17，HAMD-17）、汉密尔顿焦虑量表17项（Hamilton anxiety scale-17，HAMA-17）评分均比言语正常组高（

＜0.05）。多因素Logistic回归分析显示，年龄增大（OR=8.776，95%CI=2.479～31.069）、病变部位为左侧基底节（OR=6.430，95%CI=2.019～20.478）、MoCA评分降低（OR=3.838，95%CI=1.513～9.738）、MMSE评分降低（OR=2.672，95%CI=1.183～6.040）、PHQ-9评分升高（OR=2.399，95%CI=1.187～4.848）、HAMD-17评分升高（OR=3.575，95%CI=1.293～9.887）、HAMA-17评分升高（OR=3.261，95%CI=1.077～9.869）是卒中后基底节失语的影响因素（

＜0.05）。

结论

卒中后基底节失语患者语言功能受损，可表现出认知功能障碍及焦虑抑郁情绪，失语症的发生与年龄、左侧基底节病变、认知功能降低、焦虑抑郁情绪增加有关。

Abstract

Objective

To analyze the clinical features and influencing factors of basal ganglia aphasia after stroke.

Methods

120 patients with basal ganglia stroke admitted to the Department of Intensive Care Medicine of the First People's Hospital of Suqian City from August 2022 to May 2024 were selected as the study objects. According to whether aphasia occurred after stroke

they were divided into an aphasia group (32 cases) and a normal speech group (88 cases). The baseline data

such as clinical general data and laboratory examination indicators

were collected

and clinical language scale and neuropsychological scale were evaluated in the both groups. The clinical features of basal ganglia aphasia after stroke were analyzed

and the influencing factors of basal ganglia aphasia after stroke were analyzed by multivariate Logistic regression.

Results

There were significant differences in age and lesion site between the aphasia group and the normal speech group (

0.05).On the aphasia battery of Chinese (ABC)

Fluency

Reading

Nomenclature

Listening Comprehension

aphasia quotient

AQ score

Montreal cognitive assessment Scale (MoCA) score and Mini-Mental State examination (MMSE) score were all lower than those of the normal speech group (

0.05). Patient health questionnaire (PHQ-9) score and Hamilton depression scale-17 score of aphasia group HAMD-17 score and Hamilton anxiety scale-17 score were higher than those of the normal speech group(

0.05). Multivariate Logistic regression analysis showed that age increased (OR=8.776

95%CI= 2.479-31.069)

lesion location was left basal ganglia (OR=6.430

95%CI= 2.019-20.478)

MoCA score decreased (OR=3.838

MOCA score decreased (OR=3.838.95%CI=1.513～9.738)

MMSE score decreased (OR=2.672

95%CI=1.183～6.040)

PHQ-9 score increased (OR=2.399

95%CI=1.187～4.848)

HAMD-17 score increased (OR=3.575

95%CI= 1.293-9.887) and increased HAMA-17 score (OR=3.261

95%CI= 1.077-9.869) were the influential factors for basal ganglia aphasia after stroke (

0.05).

Conclusion

The patients with basal ganglia aphasia after stroke have impaired language function

and may show cognitive dysfunction and obvious anxiety and depression. The occurrence of aphasia is related to age

left basal ganglia lesion

reduced cognitive function

and increased anxiety and depression.

关键词

Keywords

references

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