职业噪声暴露人群额叶脑网络功能连通性研究

潘庆春; 米雪芹; 李蓓; 王媛玲; 张静; 唐晓茗; 宋小影

doi:10.3969/j.issn.1672-4933.2024.03.010

您当前的位置：

首页 >

文章列表页 >

职业噪声暴露人群额叶脑网络功能连通性研究

临床研究 | 更新时间：2024-05-30

- 职业噪声暴露人群额叶脑网络功能连通性研究
- Functional Connectivity of Frontal Brain Network in Occupational Noise-Exposed Population
- 中国听力语言康复科学杂志 2024年22卷第3期页码：264-269
- 作者机构：
  
  1.川北医学院附属医院耳鼻咽喉头颈外科南充 637000
  2.川北医学院运动医学与康复学院南充 637000
- 作者简介：
  
  潘庆春硕士主治医师；研究方向：临床听力学
  米雪芹，E-mail：1379606206@qq.com
- 基金信息：
  
  南充市社会科学研究“十四五”规划2024年度项目(NC24B212;NC24C150);川北医学院2021年度校级科研发展计划项目(CBY21-ZD01);川北医学院2023度本科教学工程立项建设项目(JG20230111);川北医学院2024年本科教学工程项目(CXSY24-27;CXSY24-23;XNFZ24-23;XNFZ24-24;XNFZ24-29)
- DOI：10.3969/j.issn.1672-4933.2024.03.010
  中图分类号： R764.43+3
- 纸质出版日期：2024-05-15，
  
  收稿日期：2024-01-13，
- 稿件说明：
移动端阅览
潘庆春,米雪芹,李蓓等.职业噪声暴露人群额叶脑网络功能连通性研究[J].中国听力语言康复科学杂志,2024,22(03):264-269.

PAN Qing-chun,MI Xue-qin,LI Bei,et al.Functional Connectivity of Frontal Brain Network in Occupational Noise-Exposed Population[J].Chinese Scientific Journal of Hearing and Speech Rehabilitation,2024,22(03):264-269.
潘庆春,米雪芹,李蓓等.职业噪声暴露人群额叶脑网络功能连通性研究[J].中国听力语言康复科学杂志,2024,22(03):264-269. DOI： 10.3969/j.issn.1672-4933.2024.03.010.

PAN Qing-chun,MI Xue-qin,LI Bei,et al.Functional Connectivity of Frontal Brain Network in Occupational Noise-Exposed Population[J].Chinese Scientific Journal of Hearing and Speech Rehabilitation,2024,22(03):264-269. DOI： 10.3969/j.issn.1672-4933.2024.03.010.

摘要

目的

采用功能性近红外线光谱技术（functional near-infrared spectroscopy，fNIRS）探讨健听的职业噪声暴露人群额叶脑网络功能连通性（functional connectivity，FC）的特征。

方法

对2023年6月～2023年11月中国某运输公司符合纳入标准的受试者进行脑网络FC、纯音听阈、声阻抗、血糖、血压及焦虑抑郁进行测试。

结果

噪声组和对照组性别、年龄、血压、血糖、医院焦虑抑郁量表-抑郁分量表（hospital anxiety and depression scale-depression subscale，HADS-D）评分无差异；噪声组医院焦虑抑郁量表-焦虑分量表（hospital anxiety and depression scale-anxiety subscale，HADS-A）评分高于对照组。噪声组的HADS-A主要集中在正常状态和临界程度，而对照组主要集中在正常状态。噪声组的额叶FC高于对照组，噪声组的额叶静息态HBO高于对照组。噪声暴露时间与额叶FC呈正相关。噪声组额叶FC与医院焦虑抑郁量表-焦虑分量表（hospital anxiety and depression scale-anxiety subscale，HADS-A）得分呈正相关。

结论

职业噪声暴露人群在听力出现异常前已经出现了脑功能改变和临床症状；随着噪声暴露时间的增加，脑网络功能改变更加明显；职业噪声暴露人群焦虑与脑网络FC的变化有一定相关性；基于fNIRS的额叶脑网络研究可为职业噪声暴露人群全脑网络的研究提供理论基础，为职业噪声人群的非听觉扩大预防工作提供依据。

Abstract

Objective

The aim of this study is to investigate the functional connectivity(FC) of frontal lobe network in occupational noise-exposed workers with normal hearing using functional near-infrared spectroscopy (fNIRS).

Methods

From June to November 2023

subjects who met the inclusion criteria in a transportation company in China were tested for brain network FC test

pure tone audiometry test

acoustic impedance test

blood glucose test

blood pressure test

anxiety and depression.

Results

There was no difference in gender

age

blood pressure

blood glucose and HADS-D between the exposed group and the control group. The HADS-A score of the exposed group was higher than that of the control group. The HADS-A of the exposed group mainly concentrated in the normal state and the critical degree

while that of the control group mainly concentrated in the normal state. The FC of the frontal lobe in the exposed group was higher than that in the control group

and the resting HBO of the frontal lobe in the exposed group was higher than that in the control group. Noise exposure time was positively correlated with FC in frontal lobe. There was A positive correlation between frontal FC and Hospital anxiety and depression scale-anxiety subscale (HDS-A) scores in the exposed group.

Conclusion

1. The brain function changes and clinical symptoms of occupational noise-exposed population occur before hearing impairment. With the increase of noise exposure time

the changes of brain network function are more obvious. 2. There is a certain correlation between anxiety and the changes of brain network FC in occupational noise exposed population. 3. The study of frontal lobe brain network based on fNIRS can provide a theoretical basis for the study of the whole brain network of occupational noise exposure population.

关键词

职业噪声暴露健听脑网络功能连通性

Keywords

Occupational noise exposureNormal hearingBrain networkFunctional connectivity

references

Vasudevamurthy S, Kumar AU. Middle Ear Muscle Reflex in Normal-Hearing Individuals with Occupational Noise Exposure[J]. Noise Health,2023,25(116):1-7.

Stokholm ZA, Bonde JP, Christensen KL, et al. Occupational noise exposure and the risk of hypertension[J]. Epidemiology,2013,24(1):135-142.

Kerns E, Masterson EA, Themann CL, et al. Cardiovascular conditions, hearing difficulty, and occupational noise exposure within US industries and occupations[J]. Am J Ind Med,2018,61(6):477-491.

Li W, Zhang H, Xiao Y, et al. Association between occupational noise exposure duration and heart rate variability among Chinese adults: The role of plasma miRNAs[J]. Environ Pollut,2023,323(0269-7491):121324.

Arjunan A, Rajan R. Noise and brain[J]. Physiol Behav,2020,227(0031-9384):113136.

Dzhambov AM, Lercher P. Road Traffic Noise Exposure and Depression/Anxiety: An Updated Systematic Review and Meta-Analysis[J]. Int J Environ Res Public Health,2019,16(21):4134.

Dzhambov AM, Tokmakova MP, Gatseva PD, et al. Community Noise Exposure and its Effect on Blood Pressure and Renal Function in Patients with Hypertension and Cardiovascular Disease[J]. Folia Med (Plovdiv),2017,59(3):344-356.

Van den Heuvel MP, Hulshoff Pol HE. Exploring the brain network: a review on resting-state fMRI functional connectivity[J]. Eur Neuropsychopharmacol,2010,20(8):519-534.

Menon B. Towards a new model of understanding - The triple network, psychopathology and the structure of the mind[J]. Med Hypotheses,2019,133(0306-9877):109385.

Kang HJ, Kang DW, Kim SS, et al. Analysis of Chronic Tinnitus in Noise-Induced Hearing Loss and Presbycusis[J]. J Clin Med,2021,10(8):1779.

Wankhar W, Srinivasan S, Sundareswaran L, et al. Role of Scoparia dulcis linn on noise-induced nitric oxide synthase (NOS) expression and neurotransmitter assessment on motor function in Wistar albino rats[J]. Biomed Pharmacother,2017,(86):475-481.

Shu Z, Wu J, Li H, et al. fNIRS-based functional connectivity signifies recovery in patients with disorders of consciousness after DBS treatment[J]. Clin Neurophysiol,2023,147(1388-2457):60-68.

Li H, Liu J, Tian S, et al. Language reorganization patterns in global aphasia-evidence from fNIRS[J]. Front Neurol,2023,13(1664-2295):1025384.

Tomasi D, Volkow ND. Association between functional connectivity hubs and brain networks[J]. Cereb Cortex,2011,21(9):2003-2013.

Martínez-Vilavella G, Pujol J, Blanco-Hinojo L, et al. The effects of exposure to road traffic noise at school on central auditory pathway functional connectivity[J]. Environ Res,2023,226(0013-9351):115574.

Alexander MP, Stuss DT. Disorders of frontal lobe functioning[J]. Semin Neurol,2000,20(4):427-437.

Pisarchik A, Chholak P, Hramov A. Brain noise estimation from MEG response to flickering visual stimulation[J]. Chaos, Solitons & Fractals: X,2019,(1):100005.

Jafari Z, Kolb BE, Mohajerani MH. Chronic traffic noise stress accelerates brain impairment and cognitive decline in mice[J]. Exp Neurol,2018,308(0014-4886):1-12.

Nußbaum R, Lucht S, Jockwitz C, et al. Associations of Air Pollution and Noise with Local Brain Structure in a Cohort of Older Adults[J]. Environ Health Perspect,2020,128(6):67012.

McEwen BS, Morrison JH. The brain on stress: vulnerability and plasticity of the prefrontal cortex over the life course[J]. Neuron,2013,79(1):16-29.

Lan Y, Roberts H, Kwan MP, et al. Transportation noise exposure and anxiety: A systematic review and meta-analysis[J]. Environ Res,2020,191(0013-9351):110118.

Hardoy MC, Carta MG, Marci AR, et al. Exposure to aircraft noise and risk of psychiatric disorders: the Elmas survey--aircraft noise and psychiatric disorders[J]. Soc Psychiatry Psychiatr Epidemiol,2005,40(1):24-26.

Bocquier A, Cortaredona S, Boutin C, et al. Is exposure to night-time traffic noise a risk factor for purchase of anxiolytic-hypnotic medication? A cohort study[J]. Eur J Public Health,2014,24(2):298-303.

Beutel ME, Jünger C, Klein EM, et al. Noise Annoyance Is Associated with Depression and Anxiety in the General Population- The Contribution of Aircraft Noise[J]. PLoS One,2016,11(5):e0155357.

Babisch W. Stress hormones in the research on cardiovascular effects of noise[J]. Noise Health,2003,5(18):1-11.

Clark C, Paunovic K. WHO Environmental Noise Guidelines for the European Region: A Systematic Review on Environmental Noise and Quality of Life, Wellbeing and Mental Health[J]. Int J Environ Res Public Health,2018,15(11):2400.

浏览量

下载量

CSCD

文章被引用时，请邮件提醒。

提交

工具集

关联资源

暂无数据