Objective

2

The clinical and audiological characteristics of unilateral acoustic neuroma patients with normal mean auditory threshold (PTA≤25 dB HL) were analyzed to provide reference for early screening and diagnosis of acoustic neuroma.

Methods

2

Thirty-two patients with unilateral acoustic neuroma with normal mean hearing threshold (32 ears) were selected as the experimental group to analyze their clinical and audiological characteristics. A total of 20 patients (32 ears) with normal average hearing threshold matching with age and genders were selected as the control group.

Results

2

Tinnitus only

tinnitus accompanied by recurrent and curable sudden hearing loss were the most common initial symptoms in patients with normal auditory threshold auditory neuroma

accounting for 50.00%

most common in people aged 30-40 years old. The abnormal rate of auditory brainstem response was 75.00% (24/32)

the abnormal rate of distortion product otoacoustic emission was 78.12% (25/32)

the abnormal rates of ipsilomedapedus sound in the affected ear and the abnormal cross acoustic stapedius reflex in the h

ealthy ear were 28.13% and 56.25%

respectively. The abnormal rates of ipsilomedapedial sound in healthy ear and cross acoustic stapedius reflex in affected ear were 6.25% and 62.50%

respectively. The audiological characteristics of the experimental and the control groups were compared and analyzed. For the Wave Ⅲ latency

Wave Ⅴ latency

Wave Ⅰ-Ⅲ interphase and Wave Ⅰ-Ⅴ interphase of auditory brainstem response in the two groups

the cross acoustic stapedius reflex of the affected ear and the healthy ear (0.5

1

2

4 kHz)

and the ipsilateral acoustic stapedius reflex of the affected ear (2 kHz)

there was a statistical difference between the two groups (

P

<

0.05)

and no statistical difference was found in the abnormal rate of distortion product otoacoustic emission between the two groups (

P

>

0.05).

Conclusion

2

Auditory brainstem response and acoustic stapedius reflex detection are helpful for the early diagnosis of acoustic neuroma

while distortion product otoacoustic emission is a highly sensitive but poorly specific detection index. For patients with unilateral tinnitus with normal mean hearing threshold in outpatient clinics

or with recurrent and curable sudden hearing loss

it is recommended to use auditory brainstem response

acoustic stapedius reflex

distortion product otoacoustic emission comprehensive assessment to provide basis for early diagnosis of acoustic neuroma.