Ototoxic substances and noise are two important factors that lead to sensorineural hearing loss
and the combined exposure of multiple factors is more serious and common in daily environment
causing the hearing loss to increase year by year. This paper reviews the research progress of hearing loss induced by ototoxic substances and noise and introduces the classification of ototoxic substances and noise
the epidemiological study of compound hearing loss
animal experiments
mechanism analysis and prevention.It summarizes the achievements
shortcomings and future directions of the present research. The paper is of great significance to understand the present situation of compound hearing loss and to guide the prevention