A Clinical Study of Audio-visual Integration Training Combined with rTMS in the Treatment of Children with Delayed Speech Development

YANG Wen-qing; DONG Hua-si; ZHANG Xiao-yuan

doi:10.3969/j.issn.1672-4933.2026.03.012

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A Clinical Study of Audio-visual Integration Training Combined with rTMS in the Treatment of Children with Delayed Speech Development

Rehabilitation Education | 更新时间：2026-07-30

- A Clinical Study of Audio-visual Integration Training Combined with rTMS in the Treatment of Children with Delayed Speech Development
- Chinese Scientific Journal of Hearing and Speech Rehabilitation Vol. 24, Issue 3, Pages: 276-280(2026)
- 作者机构：
  
  1.海淀第二十离职干部休养所北京 100040
  2.解放军总医院第四医学中心北京 100143
- 作者简介：
- 基金信息：
- DOI：10.3969/j.issn.1672-4933.2026.03.012
  CLC： R473
- Received：07 February 2025，
  
  Online First：11 May 2026，
  
  Published：15 May 2026
- 稿件说明：
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杨雯清,董华思,张晓园.视听觉统合训练联合重复经颅磁刺激治疗儿童语言发育迟缓的临床研究[J].中国听力语言康复科学杂志,2026,24(03):276-280.

YANG Wen-qing,DONG Hua-si,ZHANG Xiao-yuan.A Clinical Study of Audio-visual Integration Training Combined with rTMS in the Treatment of Children with Delayed Speech Development[J].Chinese Scientific Journal of Hearing and Speech Rehabilitation,2026,24(03):276-280.
杨雯清,董华思,张晓园.视听觉统合训练联合重复经颅磁刺激治疗儿童语言发育迟缓的临床研究[J].中国听力语言康复科学杂志,2026,24(03):276-280. DOI： 10.3969/j.issn.1672-4933.2026.03.012.

YANG Wen-qing,DONG Hua-si,ZHANG Xiao-yuan.A Clinical Study of Audio-visual Integration Training Combined with rTMS in the Treatment of Children with Delayed Speech Development[J].Chinese Scientific Journal of Hearing and Speech Rehabilitation,2026,24(03):276-280. DOI： 10.3969/j.issn.1672-4933.2026.03.012.

摘要

目的

研究视听觉统合训练联合重复经颅磁刺激（repetitive transcranial magnetic stimulation，rTMS）治疗儿童语言发育迟缓的临床疗效。

方法

选择我院2019年1月～2021年1月收治的87例语言发育迟缓患儿，采用随机数字表法分为对照组（n=43）和观察组（n=44），对照组采用常规语言训练，观察组在对照组基础上应用视听觉统合训练联合rTMS治疗，持续干预6个月。比较两组干预前后治疗效果、语言能力（verbal behavior assessment scale，ver-BAS）、口部运动功能、构音能力、发育商（developmental quotient，DQ）、神经中枢营养因子，以及家长满意度。

结果

对照组总有效率（76.74%）显著低于观察组（95.45%）（

＜0.05）。干预后，两组Ver-BAS、口部运动功能、构音能力、DQ评分均显著升高（

＜0.05），观察组显著高于对照组（

＜0.05）。两组血清脑源性神经营养因子（brain-derived neurotrophic factor，BDNF）、神经生长因子（nerve growth factor，NGF）、神经营养因子-3（neurotrophic factor-3，NT-3）、胶质细胞源性神经营养因子（glial cell-derived neurotrophic factor，GDNF）水平均升高，观察组显著高于对照组（

＜0.05）。对照组家长满意度（79.07%）显著低于观察组（97.73%）（

＜0.05）。

结论

视听觉统合训练联合rTMS可显著改善语言发育迟缓患儿语言能力、口部运动功能、构音能力，在促进患儿整体发育及神经中枢营养因子表达方面具有优势，患儿家长较满意。

Abstract

Objective

To study the clinical efficacy of audio-visual integration training combined with repetitive transcranial magnetic stimulation (rTMS) in the treatment of children with delayed language development.

Methods

87 children with language development delay treated at our hospital from January 2019 to January 2021 were selected and randomly divided into a control group (n=43) and an observation group (n=44) using a random number table. The control group received conventional language training

while the observation group received audiovisual integration training combined with rTMS on the basis of the control group. The interventions lasted for 6 months. The treatment effects before and after the intervention

verbal behavior assessment scale (Ver-BAS) scores

oral motor function scores

articulation ability scores

developmental quotient (DQ) scores

and neurocentral nutritional factors were compared between the two groups

and parental satisfaction was also investigated.

Results

The observation group had a higher overall effective rate (95.45%) than the control group (76.74%) (

0.05).Following the intervention

both groups' Ver-BAS

oral motor function

phonological ability

and DQ scores increased; the observation group's score was significantly higher than the control group's (

0.05). Serum levels of neurotrophic factor-3 (NT-3)

glial cell-derived neurotrophic factor (GDNF)

nerve growth factor (NGF)

and brain-derived neurotrophic factor (BDNF) were significantly higher in the observation group than in the control group (

0.05). The observation group (97.73%) was more satisfied than the control group (79.07%)(

0.05).

Conclusion

Visual and auditory integration training combined with rTMS can significantly improve the language ability

oral-motor function

and phonological ability of children with delayed speech development

and also has the advantage of promoting the overall development of the children and the expression of central nervous trophic factor

the effect is accurate

and the families of the children are more satisfied.

关键词

Keywords

references

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