Effects of Perinatal Infection on Hearing of Newborns and Infants

XU Min; SUN Qian; HUANG Wei; WEN Xin

doi:10.3969/j.issn.1672-4933.2025.02.009

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Effects of Perinatal Infection on Hearing of Newborns and Infants

Clinical Research | 更新时间：2026-07-11

- Effects of Perinatal Infection on Hearing of Newborns and Infants
- Chinese Scientific Journal of Hearing and Speech Rehabilitation Vol. 23, Issue 2, Pages: 145-149(2025)
- 作者机构：
  
  河北省儿童医院耳鼻咽喉科石家庄 050000
- 作者简介：
- 基金信息：
- DOI：10.3969/j.issn.1672-4933.2025.02.009
  CLC： R764.5
- Received：29 May 2024，
  
  Published：15 March 2025
- 稿件说明：
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许敏,孙倩,黄薇等.围产期感染对新生儿及婴幼儿听力的影响[J].中国听力语言康复科学杂志,2025,23(02):145-149.

XU Min,SUN Qian,HUANG Wei,et al.Effects of Perinatal Infection on Hearing of Newborns and Infants[J].Chinese Scientific Journal of Hearing and Speech Rehabilitation,2025,23(02):145-149.
许敏,孙倩,黄薇等.围产期感染对新生儿及婴幼儿听力的影响[J].中国听力语言康复科学杂志,2025,23(02):145-149. DOI： 10.3969/j.issn.1672-4933.2025.02.009.

XU Min,SUN Qian,HUANG Wei,et al.Effects of Perinatal Infection on Hearing of Newborns and Infants[J].Chinese Scientific Journal of Hearing and Speech Rehabilitation,2025,23(02):145-149. DOI： 10.3969/j.issn.1672-4933.2025.02.009.

摘要

目的

探究围产期感染对新生儿及婴幼儿听力的影响。

方法

选择2020年3月～2023年3月河北省儿童医院收治的围产期感染孕妇72例作为研究组，选择同期收治无围产期感染孕妇130例作为对照组，孕妇分娩后新生儿定期行听力筛查。比较两组新生儿出生时听力筛查情况、出生后婴幼儿听力情况，分析新生儿听力损伤影响因素。

结果

研究组出生后听力初筛、复筛未通过率均显著高于对照组（

＜0.05）；研究组3月龄时波V反应阈值及听力损伤程度均显著高于对照组（

＜0.05）；研究组随访先天性感音神经性聋发生率及听力损伤程度均高于对照组（

＜0.05）；产妇年龄、体重指数、文化程度、产次、侵入性操作、新生儿性别、分娩方式与听力损伤比较无显著差异（

＞0.05），分娩孕周、新生儿出生体重、围产期感染、新生儿高胆红素血症与听力损伤有显著差异（

＜0.05）；Spearman相关性分析显示，分娩孕周、出生体重、围产期感染、新生儿高胆红素血症等与新生儿听力损伤存在相关性（

=-0.534、0.411、0.623、0.389，

＜0.05）；多元Logistic回归分析显示，分娩孕周、新生儿出生体重、围产期感染、新生儿高胆红素血症为听力损伤影响因素（

＜0.05）。

结论

围产期感染会加重新生儿及婴幼儿听力损伤程度，是新生儿及婴幼儿听力健康的影响因素，应该重点关注，加强随访。

Abstract

Objective

To explore the effects of perinatal infection on hearing of newborns and infants.

Methods

A total of 72 pregnant women with perinatal infection admitted to the hospital from March 2020 to March 2023 were chosen as the study group. A total of 130 pregnant women without perinatal infection were selected as the control group. The newborns received hearing screening regularly after delivery. The hearing screening of newborns at birth and infants after birth was compared

and the influencing factors of neonatal hearing impairment were analyzed.

Results

The failure rate of primary screening and rescreening after birth in the study group were higher (

0.05)

and the threshold of wave V response and the degree of hearing impairment were also higher at 3 months of age (

0.05). The incidence of congenital sensorineural deafness and the degree of hearing impairment in the study group were higher than the other group (

0.05). There was no statistically significant difference in hearing impairment among different maternal age

maternal body mass index

maternal education level

delivery time

invasive operation

gender and delivery mode (

0.05). There were statistically significant differences in gestational week

birth weight

perinatal infection and neonatal hyperbilirubinemia hearing impairment (

0.05). Spearman correlation analysis showed that gestational week

birth weight

perinatal infection and neonatal hyperbilirubinemia were correlated with neonatal hearing impairment (

=-0.534

0.411

0.623

0.389

0.05). Multiple Logistic regression analysis showed that gestational week

birth weight

perinatal infection and neonatal hyperbilirubinemia were the influential factors of hearing impairment (

0.05).

Conclusions

Perinatal infection can increase the degree of hearing impairment in newborns and infants

and it is a factor affecting the hearing of newborns and infants. Attention should be paid to it and follow-up should be strengthened.

关键词

Keywords

references

Dhudasia MB , Flannery DD , Pfeifer MR , et al . Updated Guidance: Prevention and Management of Perinatal Group B Streptococcus Infection [J ] . Neoreviews , 2021 , 22 ( 3 ): 177 - 188 .

Hughes BL , Clifton RG , Rouse DJ , et al . A Trial of Hyperimmune Globulin to Prevent Congenital Cytomegalovirus Infection [J ] . N Engl J Med , 2021 , 385 ( 5 ): 436 - 444 .

Michniewicz B , Wroblewska-Seniuk K , Amara JA , et al . Hearing Impairment in Infants with Hypoxic Ischemic Encephalopathy Treated with Hypothermia [J ] . Ther Hypothermia Temp Manag , 2022 , 12 ( 1 ): 8 - 15 .

Garbaruk ES , Fedorova LA , Savenko IV , et al . Audiologicheskii skrining v detskom vozraste: dostizheniya, problemy, vozmozhnosti povysheniya effektivnosti [Childhood hearing screening: achievements, difficulties, and possible ways to improve] [J ] . Vestn Otorinolaringol , 2021 , 86 ( 1 ): 82 - 89 .

任伟 , 梁兰梅 , 谢惠源 , 等 . 先天性及围生期巨细胞病毒感染患儿的听力研究及随访 [J ] . 国际儿科学杂志 , 2020 , 47 ( 6 ): 425 - 430 .

卫生部 . 医院感染诊断标准(试行) [J ] . 中华医学杂志 , 2001 , 81 ( 5 ): 314 - 320 .

范有武 , 徐毅泷 , 詹琴锋 , 等 . 新型冠状病毒感染对听觉系统患病率的荟萃分析 [J ] . 中华耳科学杂志 , 2023 , 21 ( 6 ): 823 - 829 .

Bussé AML , Hoeve HLJ , Nasserinejad K , et al . Prevalence of permanent neonatal hearing impairment: systematic review and Bayesian meta-analysis . Int J Audiol , 2020 , 59 ( 6 ): 475 - 485 .

Fuchs FE , Pauly M , Black AP , et al . Seroprevalence of ToRCH Pathogens in Southeast Asia [J ] . Microorganisms , 2021 , 9 ( 3 ): 574 - 583 .

Wang JY , Wang YS , Shen BT . Myocarditis combined with hypertrophic cardiomyopathy: a case report [J ] . Ann Palliat Med , 2021 , 10 ( 10 ): 11203 - 11208 .

Nishida K , Fujioka K , Sugioka Y , et al . Prediction of Neurodevelopmental Impairment in Congenital Cytomegalovirus Infection by Early Postnatal Magnetic Resonance Imaging [J ] . Neonatology , 2020 , 117 ( 4 ): 460 - 466 .

武荣荣 , 周贞 , 傅国强 , 等 . 妊娠期TORCH感染对早期新生儿的影响及临床分析 [J ] . 浙江临床医学 , 2022 , 24 ( 12 ): 1843 - 1845 .

Vos B , Noll D , Whittingham J , et al . Cytomegalovirus-A Risk Factor for Childhood Hearing Loss: A Systematic Review [J ] . Ear Hear , 2021 , 42 ( 6 ): 1447 - 1461

金媛 , 陈森 , 孙宇 . 先天性巨细胞病毒感染相关耳聋研究进展 [J ] . 中华耳科学杂志 , 2021 , 19 ( 6 ): 982 - 986 .

王影 , 耿曼英 , 张慧 , 等 . 巨细胞病毒感染对婴幼儿听力及言语发育的影响 [J ] . 临床耳鼻咽喉头颈外科杂志 , 2022 , 36 ( 3 ): 163 - 166 .

韩雪梅 , 罗寒依 , 李亚婷 , 等 . 新生儿听力筛查及听力障碍影响因素分析 [J ] . 中国听力语言康复科学杂志 , 2020 , 18 ( 3 ): 175 - 177 .

Fandiño-Cárdenas M , Idrovo AJ , Velandia R , et al . Zika Virus Infection during Pregnancy and Sensorineural Hearing Loss among Children at 3 and 24 Months Post-Partum [J ] . J Trop Pediatr , 2019 , 65 ( 4 ): 328 - 335 .

平凯歌 , 耿曼英 , 张慧 , 等 . 低出生体重对婴幼儿听力及言语发育的影响 [J ] . 听力学及言语疾病杂志 , 2021 , 29 ( 3 ): 288 - 291 .

赵洪春 , 车娟 , 张肖林 , 等 . 新生儿听力筛查结果及影响因素分析和临床指导意义 [J ] . 中华耳科学杂志 , 2020 , 18 ( 4 ): 734 - 739 .

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