耳鸣评估检测方法：从临床实践到多模态整合

宫琴; 郑颖芳; 朱敏; 陈欢; 朱仁骏

doi:10.3969/j.issn.1672-4933.2025.04.005

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耳鸣评估检测方法：从临床实践到多模态整合

耳鸣研究 | 更新时间：2026-07-11

- 耳鸣评估检测方法：从临床实践到多模态整合
- Methods for Tinnitus Assessment and Detection: From Clinical Practice to Multimodal Integration
- 中国听力语言康复科学杂志 2025年23卷第4期页码：367-377
- 作者机构：
  
  1.清华大学生物医学工程学院北京 100084
  2.安徽工程大学电气工程学院安徽 241000
  3.无锡清耳话声科技有限公司江苏 214000
- 作者简介：
  
  宫琴，E-mail：gongqin@mail.tsinghua.edu.cn
- 基金信息：
  
  “十四·五”国家重点研发计划“诊疗装备与生物医用材料”耳鸣评估诊断治疗设备的研发及产业化(2023YFC2416200)
- DOI：10.3969/j.issn.1672-4933.2025.04.005
  中图分类号： R764.45
- 收稿：2025-05-19，
  
  纸质出版：2025-07-15
- 稿件说明：
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宫琴,郑颖芳,朱敏等.耳鸣评估检测方法：从临床实践到多模态整合[J].中国听力语言康复科学杂志,2025,23(04):367-377.

GONG Qin,ZHENG Ying-fang,ZHU Min,et al.Methods for Tinnitus Assessment and Detection: From Clinical Practice to Multimodal Integration[J].Chinese Scientific Journal of Hearing and Speech Rehabilitation,2025,23(04):367-377.
宫琴,郑颖芳,朱敏等.耳鸣评估检测方法：从临床实践到多模态整合[J].中国听力语言康复科学杂志,2025,23(04):367-377. DOI： 10.3969/j.issn.1672-4933.2025.04.005.

GONG Qin,ZHENG Ying-fang,ZHU Min,et al.Methods for Tinnitus Assessment and Detection: From Clinical Practice to Multimodal Integration[J].Chinese Scientific Journal of Hearing and Speech Rehabilitation,2025,23(04):367-377. DOI： 10.3969/j.issn.1672-4933.2025.04.005.

摘要

耳鸣是一种病因复杂且具有高度异质性的耳科疑难病症。耳鸣的评估检测一直是临床诊疗和科学研究中的难点。主观量表、心理声学、客观标志物的评估检测方法从不同侧面为耳鸣的评估、诊断、康复效果的研究提供了标准化的辅助手段。本文综述了在临床研究中的耳鸣量表、心理声学和客观标志物在耳鸣临床评估、检测、疗效监测和机理机制研究中的价值，并对耳鸣客观定量诊疗标志物的发展趋势进行了展望。

Abstract

Tinnitus is a complicated and highly heterogeneous ear disease. The assessment and detection of tinnitus has always been a difficult problem in clinical diagnosis and scientific research. Subjective scales

psychoacoustics and objective markers provide standardized multifaceted for the assessment

diagnosis and rehabilitation of tinnitus. Here

we reviewed and summarized the application of tinnitus scale

psychoacoustics and objective markers in clinical evaluation

matching

efficacy monitoring and mechanism research of tinnitus.We also discussed the outlook of the objective and quantitative diagnosis of tinnitus and its treatment markers.

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references

Langguth B , Ridder DD , Schlee W , et al . Tinnitus: Clinical Insights in Its Pathophysiology-A Perspective [J ] . Journal of the Association for Research in Otolaryngology: JARO , 2024 , 25 ( 3 ): 249 - 258 .

Baguley D , McFerran D , Hall D . Tinnitus [J ] . The Lancet , 2013 , 382 ( 9904 ): 1600 - 1607 .

McFerran J D , Stockdale D , Holme R , et al . Why Is There No Cure for Tinnitus? [J ] . Frontiers in Neuroscience , 2019 , 13 ( 6 ): 802 - 815 .

Watts EJ , Fackrell K , Smith S , et al . Why Is Tinnitus a Problem? A Qualitative Analysis of Problems Reported by Tinnitus Patients [J ] . Trends in Hearing , 2018 , 22 : 2331216518812250 .

Kleinjung T , Langguth B . Avenue for Future Tinnitus Treatments [J ] . Otolaryngologic Clinics of North America , 2020 , 53 ( 4 ): 667 - 683 .

Negrila-Mezei A , Enache R , Sarafoleanu C . Tinnitus in elderly population: clinic correlations and impact upon QoL [J ] . Journal of Medicine and Life , 2011 , 4 ( 4 ): 412 - 416 .

Langguth B , Kreuzer MP , Kleinjung T , et al . Tinnitus: causes and clinical management [J ] . The Lancet. Neurology , 2013 , 12 ( 9 ): 920 - 930 .

谭君颖 , 张剑宁 , 李明 . 耳鸣心理声学特征与一般环境声掩蔽耳鸣效果的关系 [J ] . 听力学及言语疾病杂志 , 2015 , 23 ( 1 ): 69 - 72 .

Bhatt JM , Bhattacharyya N , Lin HW . Relationships between tinnitus and the prevalence of anxiety and depression [J ] . The Laryngoscope , 2017 , 127 ( 2 ): 466 - 469 .

Stockdale D , Mcferran D , Brazier P , et al . An economic evaluation of the healthcare cost of tinnitus management in the UK [J ] . BMC health services research , 2017 , 17 ( 1 ): 577 - 586 .

Linnett S . The epidemiology of tinnitus [J ] . Audiological Medicine , 2004 , 2 ( 1 ): 8 - 17 .

Coles ARR . Epidemiology of tinnitus: (1) prevalence [J ] . The Journal of Laryngology, Rhin ology, and Otology , 2011 , 98 ( S9 ): 7 - 15 .

Tunkel DE , Bauer CA , Sun GH , et al . Clinical practice guideline: tinnitus [J ] . Otolaryngology--Head and Neck Surgery , 2014 , 151 ( S2 ): S1 - S40 .

Newman CW , Jacobson GP , Spitzer JB . Development of the Tinnitus Handicap Inventory [J ] . Archives of Otolaryngology--Head & Neck Surgery , 1996 , 122 ( 2 ): 143 - 148 .

Aksoy S , Firat Y , Alpar R . The Tinnitus Handicap Inventory: a study of validity and reliability [J ] . The International Tinnitus Journal , 2007 , 13 ( 2 ): 94 - 98 .

Meikle MB , Henry JA , Griest SE , et al . The tinnitus functional index: development of a new clinical measure for chronic, intrusive tinnitus [J ] . Ear and Hearing , 2012 , 33 ( 2 ): 153 - 176 .

Hallam RS , Jakes SC , Hinchcliffe R . Cognitive variables in tinnitus annoyance [J ] . The British Journal of Clinical Psychology , 1988 , 27 ( 3 ): 213 - 222 .

Kam ACS , Cheung APP , Chan PYB , et al . Psychometric properties of a Chinese (Cantonese) version of the Tinnitus Questionnaire [J ] . International Journal of Audiology , 2009 , 48 ( 8 ): 568 - 575 .

Wilson PH , Henry J , Bowen M , et al . Tinnitus reaction questionnaire: psychometric properties of a measure of distress associated with tinnitus [J ] . Journal of Speech and Hearing Research , 1991 , 34 ( 1 ): 197 - 201 .

Tyler RS , Baker LJ . Difficulties experienced by tinnitus sufferers [J/OL ] . The Journal of Speech and Hearing Disorders , 1983 , 48 ( 2 ): 150 - 154 .

Kuk FK , Tyler RS , Russell D , et al . The psychometric properties of a tinnitus handicap questionnaire [J ] . Ear and Hearing , 1990 , 11 ( 6 ): 434 - 445 .

Cima RFF , Mazurek B , Haider H , et al . A multidisciplinary European guideline for tinnitus: diagnostics, assessment, and treatment [J ] . HNO , 2019 , 67 ( Suppl 1 ): 10 - 42 .

Adamchic I , Langguth B , Hauptmann C , et al . Psychometric evaluation of visual analog scale for the assessment of chronic tinnitus [J ] . American Journal of Audiology , 2012 , 21 ( 2 ): 215 - 225 .

Raj-koziak D , Gos E , Świerniak W , et al . Relationship Between Tinnitus Loudness Measure by Visual Analogue Scale and Psychoacoustic Matching of Tinnitus Loudness [J ] . Otology & Neurotology , 2019 , 40 ( 40 ): 16 - 21 .

刘蓬 , 李明 . 对耳鸣疗效评价的思考 [J ] . 中华耳鼻咽喉头颈外科杂志 , 2008 , 43 ( 9 ): 710 - 713 .

刘蓬 , 龚慧涵 , 阮紫娟 . 耳鸣严重程度评估方法的研究 [J ] . 中华耳科学杂志 , 2009 , 7 ( 3 ): 186 - 190 .

Buysse DJ , Reynolds CF , Monk TH , et al . The Pittsburgh Sleep Quality Index: a new instrument for psychiatric practice and research [J ] . Psychiatry Research , 1989 , 28 ( 2 ): 193 - 213 .

Baguley D , Andersson G , Mcferran D , et al . Tinnitus: A Multidisciplinary Approach [M ] . Chichester :0 John Wiley & Sons , Ltd , 2013 . 1 - 336 .

Newman CW , Sandridge SA , Jacobson GP . Psychometric adequacy of the Tinnitus Handicap Inventory (THI) for evaluating treatment outcome [J ] . Journal of the American Academy of Audiology , 1998 , 9 ( 2 ): 153 - 160 .

Mccombe A , Baguley D , Coles R , et al . Guidelines for the grading of tinnitus severity: the results of a working group commissioned by the British Association of Otolaryngologists, Head and Neck Surgeons, 1999 [J ] . Clinical Otolaryngology and Allied Sciences , 2001 , 26 ( 5 ): 388 - 393 .

Boecking B , Brueggemann P , Kleinjung T , et al . All for One and One for All? - Examining Convergent Validity and Responsiveness of the German Versions of the Tinnitus Questionnaire (TQ), Tinnitus Handicap Inventory (THI), and Tinnitus Functional Index (TFI) [J ] . Frontiers in Psychology , 2021 , 12 ( 5 ): 37 - 47 .

梁才全 , 查旭东 , 王天宇 , 等 . 声掩蔽疗法对舰艇官兵耳鸣患者的效果评价 [J ] . 海军医学杂志 , 2023 , 44 ( 3 ): 222 - 226 .

Eça FT , Rosa C , Santos JM , et al . Assessing the efficacy of a novel bone conduction tinnitus suppression device: a 30-day pilot study on clinical and audiological outcomes [J ] . European Archives of Oto-Rhino-Laryngology , 2025 , (prepublish):1- 6 .

Mcneill C , Távora-vieira D , Alnafjan F , et al . Tinnitus pitch, masking, and the effectiveness of hearing aids for tinnitus therapy [J ] . International Journal of Audiology , 2012 , 51 ( 12 ): 914 - 919 .

Wilson P H , Henry J , Bowen M , et al . Tinnitus reaction questionnaire: psychometric properties of a measure of distress associated with tinnitus [J ] . Speech Hear Res , 1991 , 34 ( 1 ): 197 - 201 .

Tyler Richard S , Christina S , Haihong J , et al . Tinnitus Activities Treatment with Total and Partial Masking [J ] . Journal of the American Academy of Audiology , 2021 , 32 ( 8 ): 501 - 509 .

Jun HJ , Yoo IW , Hwang SJ , et al . Validation of a Korean Version of the Tinnitus Handicap Questionnaire [J ] . Clinical and Experimental Otorhinolaryngology , 2015 , 8 ( 3 ): 198 - 201 .

刘蓬 . 耳鸣评价量表的研发思路 [J ] . 中国听力语言康复科学杂志 , 2018 , 16 ( 5 ): 330 - 333 .

刘蓬 , 郑芸 . 耳鸣评价量表的临床应用 [J ] . 中国听力语言康复科学杂志 , 2018 , 16 ( 6 ): 411 - 415 .

潘庆春 , 李蓓 , 冯燚源 . 短期多元整合声对慢性主观性耳鸣患者的疗效及对大脑皮层神经活动的影响 [J ] . 中华耳科学杂志 , 2025 , 23 ( 2 ): 228 - 233 .

Langguth B , Goodey R , Azevedo A , et al . Consensus for tinnitus patient assessment and treatment outcome measurement: Tinnitus Research Initiative meeting, Regensburg, July 2006 [J ] . Progress in Brain Research , 2007 , 166 ( 10 ): 525 - 536 .

Langguth B , Kleinjung T , Schlee W , et al . Tinnitus Guidelines and Their Evidence Base [J ] . Journal of Clinical Medicine , 2023 , 12 ( 9 ): 3087 - 3112 .

王香香 , 熊海霞 , 张培丽 , 等 . 听力正常者耳鸣严重程度影响因素初步分析 [J ] . 听力学及言语疾病杂志 , 2025 , 33 ( 2 ): 140 - 144 .

陈红 , 张小莉 , 沈晓辉 , 等 . 声刺激联合认知行为治疗慢性耳鸣的初步探讨 [J ] . 中国耳鼻咽喉颅底外科杂志 , 2024 , 30 ( 2 ): 77 - 84 .

田亚云 , 李刚 , 王铭维 , 等 . 脉冲电磁场治疗原发性失眠临床疗效分析 [J ] . 中国现代神经疾病杂志 , 2023 , 23 ( 8 ): 709 - 715 .

徐鸥 , 齐培 , 祝绮莎 . 认知行为疗法联合虚拟现实技术治疗青少年失眠症患者的效果研究 [J ] . 中国全科医学 , 2022 , 25 ( 11 ): 1378 - 1382 .

陈红胜 , 陆小净 , 梅凌云 , 等 . 早期噪声性听力损失伴耳鸣患者的掩蔽效果分析 [J ] . 临床耳鼻咽喉头颈外科杂志 , 2015 , 29 ( 1 ): 75 - 78 .

蔡跃新 , 孙映凤 , 杨海弟 , 等 . 个性化切迹音乐治疗主观性耳鸣的初步观察 [J ] . 中华耳科学杂志 , 2017 , 15 ( 4 ): 465 - 470 .

Kutyba J , Gos E , Jędrzejczak WW , et al . Effectiveness of tinnitus therapy using a mobile application [J/OL ] . European archives of oto-rhino-laryngology , 2021 , 279 ( 3 ): 1257 - 1267 .

Chen Q , Lv H , Wang Z , et al . Pretreatment intranetwork connectivity can predict the outcomes in idiopathic tinnitus patients treated with sound therapy [J ] . Human Brain Mapping , 2021 , 42 ( 14 ): 4762 - 4776 .

Zeman F , Koller M , Figueiredo R , et al . Tinnitus handicap inventory for evaluating treatment effects: which changes are clinically relevant? [J/OL ] . Otolaryngology--Head and Neck Surgery , 2011 , 145 ( 2 ): 282 - 287 .

Henry JA , Griest S , Thielman E , et al . Tinnitus Functional Index: Development, validation, outcomes research, and clinical application [J ] . Hearing Research , 2016 , 334 ( 6 ): 58 - 64 .

Henry JA , Zaugg TL , Schechter MA . Clinical guide for audiologic tinnitus management II: Treatment [J ] . American Journal of Audiology , 2005 , 14 ( 1 ): 49 - 70 .

Tyler RS , Conrad-armes D . The determination of tinnitus loudness considering the effects of recruitment [J ] . Journal of Speech and Hearing Research , 1983 , 26 ( 1 ): 59 - 72 .

Norena A , Micheyl C , Chéry-croze S , et al . Psychoacoustic characterization of the tinnitus spectrum: implications for the underlying mechanisms of tinnitus [J ] . Audiology & Neuro-Otology , 2002 , 7 ( 6 ): 358 - 369 .

Roberts LE , Moffat G , Bosnyak DJ . Residual inhibition functions in relation to tinnitus spectra and auditory threshold shift [J/OL ] . Acta Oto-Laryngologica . Supplementum, 2006 , 12 ( 556 ): 27 - 33 .

田如如 , 刁明芳 , 田芳洁 , 等 . 定制音乐对慢性特发性耳鸣疗效的初步分析 [J ] . 中华耳鼻咽喉头颈外科杂志 , 2017 , 52 ( 5 ): 343 - 348 .

Mahboubi H , Ziai K , Brunworth J , et al . Accuracy of tinnitus pitch matching using a web-based protocol [J/OL ] . The Annals of Otology, Rhinology, and Laryngology, 2012 , 121 ( 10 ): 671 - 674 .

Henry JA , Flick CL , Gilbert A , et al . Comparison of two computer-automated procedures for tinnitus pitch matching [J ] . Journal of Rehabilitation Research and Development , 2001 , 38 ( 5 ): 557 - 566 .

Henry JA , Flick CL , Gilbert A , et al . Comparison of manual and computer-automated procedures for tinnitus pitch-matching [J ] . Journal of Rehabilitation Research and Development , 2004 , 41 ( 2 ): 121 - 138 .

Feldmann H . Homolateral and contralateral masking of tinnitus by noise-bands and by pure tones [J ] . Audiology , 1971 , 10 ( 3 ): 138 - 144 .

Roberts LE . Residual inhibition [J ] . Progress in Brain Research , 2007 , 166 ( 10 ): 487 - 495 .

Roberts LE , Moffat G , Baumann M , et al . Residual inhibition functions overlap tinnitus spectra and the region of auditory threshold shift [J/OL ] . Journal of the Association for Research in Otolaryngology: JARO , 2008 , 9 ( 4 ): 417 - 435 .

Fournier P , Cuvillier AF , Gallego S , et al . A New Method for Assessing Masking and Residual Inhibition of Tinnitus [J ] . Trends in Hearing , 2018 , 22 ( 2 ): 1 - 19 .

许轶 , 周慧芳 , 杨东 . 耳鸣掩蔽曲线与掩蔽治疗效果关系的临床观察 [J ] . 临床耳鼻咽喉头颈外科杂志 , 2009 , 23 ( 13 ): 588 - 590 .

杨毓梅 , 彭玉成 , 叶青 , 等 . 耳鸣测定法评价耳鸣疗效 [J ] . 临床耳鼻咽喉科杂志 , 2001 , 15 ( 07 ): 320 - 321 .

Kamalski DM , Hoekstra CE , Van Zanten BG , et al . Measuring disease-specific health-related quality of life to evaluate treatment outcomes in tinnitus patients: a systematic review [J ] . Otolaryngology-Head and Neck Surgery , 2010 , 143 ( 2 ): 181 - 185 .

Hoare DJ , Gander PE , Collins L , et al . Management of tinnitus in English NHS audiology departments: an evaluation of current practice [J ] . Journal of Evaluation in Clinical Practice , 2012 , 18 ( 2 ): 326 - 334 .

Houdayer E , Teggi R , Velikova S , et al . Involvement of cortico-subcortical circuits in normoacousic chronic tinnitus: A source localization EEG study [J ] . Clinical Neurophysiology , 2015 , 126 ( 12 ): 2356 - 2365 .

黄海云 , 蔡跃新 , 冯学技 , 等 . 基于脑电信号的耳鸣患者静息态频谱图及注意力研究 [J ] . 生物医学工程学杂志 , 2021 , 38 ( 3 ): 492 - 497 .

Riha C , Güntensperger D , Kleinjung T , et al . Accounting for Heterogeneity: Mixed-Effects Models in Resting-State EEG Data in a Sample of Tinnitus Sufferers [J ] . Brain Topography , 2020 , 33 ( 4 ): 413 - 424 .

Delb W , Strauss DJ , Low YF , et al . Alterations in Event Related Potentials (ERP) associated with tinnitus distress and attention [J/OL ] . Applied Psychophysiology and Biofeedback , 2008 , 33 ( 4 ): 211 - 221 .

Moazami-goudarzi M , Michels L , Weisz N , et al . Temporo-insular enhancement of EEG low and high frequencies in patients with chronic tinnitus. QEEG study of chronic tinnitus patients [J ] . BMC neuroscience , 2010 , 11 ( 1 ): 40 - 52 .

Balkenhol T , Wallhäusser-franke E , Delb W . Psychoacoustic tinnitus loudness and tinnitus-related distress show different associations with oscillatory brain activity [J ] . PloS One , 2013 , 8 ( 1 ): e53180 - e53193 .

Asadpour A , Alavi A , Jahed M , et al . Cognitive Memory Comparison Between Tinnitus and Normal Cases Using Event-Related Potentials [J/OL ] . Frontiers in Integrative Neuroscience , 2018 , 12 ( 10 ): 48 - 94 .

Lorenz I , Müller N , Schlee W , et al . Loss of alpha power is related to increased gamma synchronization-A marker of reduced inhibition in tinnitus? [J ] . Neuroscience Letters , 2009 , 453 ( 3 ): 225 - 228 .

Weisz N , Dohrmann K , Elbert T . The relevance of spontaneous activity for the coding of the tinnitus sensation [J ] . Progress in Brain Research , 2007 , 166 ( 10 ): 61 - 70 .

Feng X , Bao X , Huang H , et al . Frontal gamma-alpha ratio reveals neural oscillatory mechanism of attention shifting in tinnitus [J ] . iScience , 2025 , 28 ( 3 ): 111929 - 111943 .

Sendesen E , Erbil N , Türkyilmaz MD . The mismatch negativity responses of individuals with tinnitus with normal extended high-frequency hearing-is it possible to use mismatch negativity in the evaluation of tinnitus? [J ] . European archives of oto-rhino-laryngology , 2022 , 279 ( 7 ): 3425 - 3434 .

Santos Filha VAV dos , Matas CG . Late Auditory evoked potentials in individuals with tinnitus [J ] . Brazilian Journal of Otorhinolaryngology , 2010 , 76 ( 2 ): 263 - 270 .

Cardon E , Vermeersch H , Joossen I , et al . Cortical auditory evoked potentials, brain signal variability and cognition as biomarkers to detect the presence of chronic tinnitus [J ] . Hearing Research , 2022 , 420 ( 3 ): 108489 - 108500 .

Singh R , Chatterjee N , Chatterjee I . Exploring P300 Responses in Tinnitus: Linking Cognitive and Audiological Assessments [J ] . Indian Journal of Otolaryngology and Head and Neck Surgery , 2025 , 77 ( 3 ): 1392 - 1400 .

Sadeghijam M , Moossavi A , Akbari M , et al . Effect of tinnitus distress on auditory steady-state response amplitudes in chronic tinnitus sufferers [J ] . Journal of Clinical Neuroscience , 2022 , 97 ( 1 ): 49 - 55 .

Diesch E , Andermann M , Flor H , et al . Interaction among the components of multiple auditory steady-state responses: enhancement in tinnitus patients, inhibition in controls [J ] . Neuroscience , 2010 , 167 ( 2 ): 540 - 553 .

Herdman AT , Stapells DK . Auditory steady-state response thresholds of adults with sensorineural hearing impairments [J ] . International Journal of Audiology , 2003 , 42 ( 5 ): 237 - 248 .

Ghasemahmad Z , Mahmoudian S , Gavazzi D , et al . Enhanced 40 and 80 Hz Auditory Steady State Responses in Idiopathic Tinnitus[A/OL] . http://medrxiv.org/lookup/doi/10.1101/2024.03.02.24303654.2025-05-10 http://medrxiv.org/lookup/doi/10.1101/2024.03.02.24303654.2025-05-10 .

De Ridder D , Vanneste S , Langguth B , et al . Thalamocortical Dysrhythmia: A Theoretical Update in Tinnitus [J ] . Frontiers in Neurology , 2015 , 6 ( 6 ): 124 - 137 .

Adjamian P , Hall DA , Palmer AR , et al . Neuroanatomical abnormalities in chronic tinnitus in the human brain [J ] . Neuroscience and Biobehavioral Reviews , 2014 , 45 ( 9 ): 119 - 133 .

Sereda M , Adjamian P , Edmondson-jones M , et al . Auditory evoked magnetic fields in individuals with tinnitus [J ] . Hearing Research , 2013 , 302 ( 4 ): 50 - 59 .

Mühlau M , Rauschecker JP , Oestreicher E , et al . Structural brain changes in tinnitus [J ] . Cerebral Cortex , 2006 , 16 ( 9 ): 1283 - 1288 .

Chen YC , Zhang J , Li XW , et al . Aberrant spontaneous brain activity in chronic tinnitus patients revealed by resting-state functional MRI [J ] . NeuroImage. Clinical , 2014 , 6 ( 9 ): 222 - 228 .

Arnold W , Bartenstein P , Oestreicher E , et al . Focal metabolic activation in the predominant left auditory cortex in patients suffering from tinnitus: a PET study with [18F] deoxyglucose [J ] . ORL J Otorhinolaryngol Relat Spec , 1996 , 58 ( 4 ): 195 - 199 .

Isler B , Von Burg N , Kleinjung T , et al . Lower glutamate and GABA levels in auditory cortex of tinnitus patients: a 2D-JPRESS MR spectroscopy study [J ] . Scientific Reports , 2022 , 12 ( 1 ): 4068 - 4082 .

Heijneman KM , De Kleine E , Wiersinga-post E , et al . Can the tinnitus spectrum identify tinnitus subgroups? [J/OL ] . Noise & Health , 2013 , 15 ( 63 ): 101 - 106 .

Lonsbury-martin BL , Martin GK . The clinical utility of distortion-product otoacoustic emissions [J/OL ] . Ear and Hearing , 1990 , 11 ( 2 ): 144 - 154 .

Sztuka A , Pospiech L , Gawron W , et al . DPOAE in estimation of the function of the cochlea in tinnitus patients with normal hearing [J/OL ] . Auris, Nasus, Larynx, 2010 , 37 ( 1 ): 55 - 60 .

Bramhall NF , Konrad-martin D , Mcmillan GP . Tinnitus and Auditory Perception After a History of Noise Exposure: Relationship to Auditory Brainstem Response Measures [J/OL ] . Ear and Hearing , 2018 , 39 ( 5 ): 881 - 894 .

Therdphaothai J , Atipas S , Suvansit K , et al . A Randomized, Controlled Trial of Notched Music Therapy for Tinnitus Patients [J/OL ] . The Journal of International Advanced Otology , 2021 , 17 ( 3 ): 221 - 227 .

Shim HJ , Kwak MY , An YH , et al . Feasibility and Safety of Transcutaneous Vagus Nerve Stimulation Paired with Notched Music Therapy for the Treatment of Chronic Tinnitus [J/OL ] . Journal of Audiology & Otology , 2015 , 19 ( 3 ): 159 - 167 .

Haab L , Lehser C , Corona-strauss FI , et al . Implementation and Long-Term Evaluation of a Hearing Aid Supported Tinnitus Treatment Using Notched Environmental Sounds [J/OL ] . IEEE journal of translational engineering in health and medicine , 2019 , 7 : 1600109 - 1600109 .

Teismann H , Okamoto H , Pantev C Short and intense tailor-made notched music training against tinnitus: the tinnitus frequency matters [J/OL ] . PloS ONE , 2011 , 6 ( 9 ): e24685 - e24693 .

Stein A , Engell A , Lau P , et al . Enhancing inhibition-induced plasticity in tinnitus--spectral energy contrasts in tailor-made notched music matter [J ] . PloS ONE , 2015 , 10 ( 5 ): 1 - 18 .

陈泓钰 , 张心苑 , 郑亿庆 , 等 . 音乐联合认知行为治疗主观性耳鸣疗效及静息态脑电的源定位分析 [J ] . 中华耳科学杂志 , 2020 , 18 ( 6 ): 1045 - 1049 .

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