人工耳蜗在脑白质改变合并听力损失儿童中的应用现状

王铭点; 李原

doi:10.3969/j.issn.1672-4933.2025.02.016

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人工耳蜗在脑白质改变合并听力损失儿童中的应用现状

综述 | 更新时间：2026-07-11

- 人工耳蜗在脑白质改变合并听力损失儿童中的应用现状
- Current Status of Cochlear Implantation in Children with White Matter Changes and Sensorineural Hearing Loss
- 中国听力语言康复科学杂志 2025年23卷第2期页码：180-184
- 作者机构：
  
  1.中日友好医院耳鼻喉头颈外科北京 100029
  2.北京协和医学院/中国医学科学院北京 100730
- 作者简介：
  
  王铭点硕士在读；研究方向：人工耳蜗植入
  李原，E-mail：yuanli0702@263.net
- 基金信息：
  
  中央高水平医院临床科研业务费资助（2023-NHLHCRF-PY-02;2024-NHLHCRF-PYⅡ-03
- DOI：10.3969/j.issn.1672-4933.2025.02.016
  中图分类号： R764.43
- 收稿：2024-12-03，
  
  纸质出版：2025-03-15
- 稿件说明：
移动端阅览
王铭点,李原.人工耳蜗在脑白质改变合并听力损失儿童中的应用现状[J].中国听力语言康复科学杂志,2025,23(02):180-184.

WANG Ming-dian,LI Yuan.Current Status of Cochlear Implantation in Children with White Matter Changes and Sensorineural Hearing Loss[J].Chinese Scientific Journal of Hearing and Speech Rehabilitation,2025,23(02):180-184.
王铭点,李原.人工耳蜗在脑白质改变合并听力损失儿童中的应用现状[J].中国听力语言康复科学杂志,2025,23(02):180-184. DOI： 10.3969/j.issn.1672-4933.2025.02.016.

WANG Ming-dian,LI Yuan.Current Status of Cochlear Implantation in Children with White Matter Changes and Sensorineural Hearing Loss[J].Chinese Scientific Journal of Hearing and Speech Rehabilitation,2025,23(02):180-184. DOI： 10.3969/j.issn.1672-4933.2025.02.016.

摘要

对于助听器干预3～6个月无效的重度-极重度双侧感音神经性聋（sensorineural hearing loss，SNHL），人工耳蜗植入（CI）是全球公认的最佳治疗方式之一。但CI术后疗效受多种因素影响，累及听觉的脑白质改变（white matter changes，WMC）是重要影响因素之一。6%～22%的语前聋CI候选者合并WMC。由于遗传因素或围产期各种原因导致髓鞘发育不良或脱髓鞘病变，若累及听觉传导通路则会影响CI效果。近20年，很多学者对合并WMC的语前聋儿童的CI效果进行了探索，本文对该类患儿CI的适应证及其术后听觉言语康复效果进行综述，为特殊病例人工耳蜗植入提供参考。

Abstract

For severe-to-profound bilateral sensorineural hearing loss (SNHL) that has not responded to hearing aid intervention for 3-6 months

cochlear implantation (CI) is one of the best treatments recognized worldwide. However

the efficacy of CI surgery is affected by many factors

and white matter changes (WMC) affecting hearing is one of the important influencing factors. 6-22% of prelingually deaf CI candidates have WMC. Myelin dysplasia or demyelinating lesions caused by genetic factors or various perinatal reasons will affect the CI effect if the auditory conduction pathway is involved. In the past two decades

many scholars have conducted meaningful explorations on the CI effect of prelingually deaf children with WMC. This article will review the indications for CI in such children and the effects of postoperative hearing and speech rehabilitation

and provide a reference for cochlear implantation in special cases.

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