听皮层功能的神经电生理学评估方法研究进展

钟旻璇; 杨崇灵; 唐菲; 郭维维; 吕萍; 刘军

doi:10.3969/j.issn.1672-4933.2025.01.025

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听皮层功能的神经电生理学评估方法研究进展

继续教育 | 更新时间：2026-07-11

- 听皮层功能的神经电生理学评估方法研究进展
- Research Progress on Neuroelectrophysiological Evaluation Methods of Auditory Cortex Function
- 中国听力语言康复科学杂志 2025年23卷第1期页码：104-108
- 作者机构：
  
  1.川北医学院/川北医学院附属医院耳鼻咽喉头颈外科南充 637000
  2.解放军总医院第六医学中心耳鼻咽喉头颈外科医学部/听觉与平衡觉全国重点实验室/国家耳鼻咽喉疾病临床医学研究中心/聋病教育部重点实验室北京 100048
  3.解放军总医院第七医学中心耳鼻咽喉头颈外科北京 100700
- 作者简介：
  
  钟旻璇在读硕士；研究方向：临床听力学、助听器效果评估、人工耳蜗术前筛查及术后疗效评估
  刘军，E-mail：liujunent@126.com
- 基金信息：
  
  北京市科技计划首都市民健康项目培育基金(Z131100004013019);解放军总医院临床科研扶持基金课题(2012FC-TSYS-4017);解放军总医院科技创新基金项目(06ZY13);国家自然科学基金面上项目(819708901011106);四川省重点研发计划(2023YFG0282)
- DOI：10.3969/j.issn.1672-4933.2025.01.025
  中图分类号： R764
- 收稿：2024-11-24，
  
  纸质出版：2025-01-15
- 稿件说明：
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钟旻璇,杨崇灵,唐菲等.听皮层功能的神经电生理学评估方法研究进展[J].中国听力语言康复科学杂志,2025,23(01):104-108.

ZHONG Min-xuan,YANG Chong-ling,TANG Fei,et al.Research Progress on Neuroelectrophysiological Evaluation Methods of Auditory Cortex Function[J].Chinese Scientific Journal of Hearing and Speech Rehabilitation,2025,23(01):104-108.
钟旻璇,杨崇灵,唐菲等.听皮层功能的神经电生理学评估方法研究进展[J].中国听力语言康复科学杂志,2025,23(01):104-108. DOI： 10.3969/j.issn.1672-4933.2025.01.025.

ZHONG Min-xuan,YANG Chong-ling,TANG Fei,et al.Research Progress on Neuroelectrophysiological Evaluation Methods of Auditory Cortex Function[J].Chinese Scientific Journal of Hearing and Speech Rehabilitation,2025,23(01):104-108. DOI： 10.3969/j.issn.1672-4933.2025.01.025.

摘要

植入年龄和听觉剥夺时间是影响先天性聋患者人工耳蜗植入（CI）后听觉和言语康复效果的重要因素，这可能与不同年龄听皮层功能水平有关，听皮层功能评估在CI术前筛查、术后疗效评估，以及神经、精神和心理学相关疾病研究中具有重要意义。听皮层功能评估方法包括神经电生理学、形态学、功能影像学、分子生物学等方面，其中神经电生理学方法操作简单且无创，主要包括基于脑电图（electroencephalography，EEG）的皮层听觉诱发电位（cortical auditory evoked potential，CAEP），如P1-N1-P2波和失匹配负波（mismatch negative，MMN）等，以及基于脑磁图（magnetoencephalography，MEG）的听觉诱发磁场（auditory evoked field，AEF），但AEF检测设备昂贵、操作复杂、环境要求高，应用较少。本文将对听皮层功能的神经电生理学评估方法及其研究进展进行综述。

Abstract

Auditory deprivation time and implantation age are important factors affecting the auditory and speech rehabilitation outcomes of cochlear implantation (CI) in patients with congenital deafness possibly associated with the functional level of the auditory cortex at different developmental stages. In terms of predicting preoperative efficacy

evaluating postoperative efficacy of CI

and conducting research on neurological

psychiatric

and psychological related diseases

the functional evaluation of the auditory cortex is essential. Methods for evaluating auditory cortex function encompass neuroelectrophysiology

morphology

functional imaging

and molecular biology. The neuroelectrophysiological methods have characteristics such as simplicity in operation and non-invasiveness

mainly including cortical auditory evoked potential (CAEP) based on electroencephalography (EEG)

such as P1-N1-P2 waves and mismatch negative (MMN)

and auditory evoked field (AEF) based on magnetoencephalography (MEG). However

AEF is less applied due to its costly detection equipment

complex operation

and stringent environmental requirements. This article will review neuroelectrophysiological evaluation methods and the research progress in auditory cortex function.

关键词

Keywords

references

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