膳食补充剂对耳鸣的影响

费樱平; 郑芸; 卢兢哲

doi:10.3969/j.issn.1672-4933.2026.03.024

您当前的位置：

首页 >

文章列表页 >

膳食补充剂对耳鸣的影响

短篇报道 | 更新时间：2026-05-25

- 膳食补充剂对耳鸣的影响
- Effect of Dietary Supplements on Tinnitus
- 中国听力语言康复科学杂志 2026年24卷第3期页码：334-336
- 作者机构：
  
  四川大学华西医院耳鼻咽喉头颈外科成都 610041
- 作者简介：
  
  费樱平博士主管技师；研究方向：临床听力学
  郑芸，E-mail：1141679315@qq.com
- 基金信息：
  
  四川省卫计委项目“耳鸣诊断与康复规范的临床研究”(0040205301F69)
- DOI：10.3969/j.issn.1672-4933.2026.03.024
  中图分类号： R764.45
- 收稿：2025-04-22，
  
  纸质出版：2026-05-15
- 稿件说明：
移动端阅览
费樱平,郑芸,卢兢哲.膳食补充剂对耳鸣的影响[J].中国听力语言康复科学杂志,2026,24(03):334-336.

FEI Ying-ping,ZHENG Yun,LU Jing-zhe.Effect of Dietary Supplements on Tinnitus[J].Chinese Scientific Journal of Hearing and Speech Rehabilitation,2026,24(03):334-336.
费樱平,郑芸,卢兢哲.膳食补充剂对耳鸣的影响[J].中国听力语言康复科学杂志,2026,24(03):334-336. DOI： 10.3969/j.issn.1672-4933.2026.03.024.

FEI Ying-ping,ZHENG Yun,LU Jing-zhe.Effect of Dietary Supplements on Tinnitus[J].Chinese Scientific Journal of Hearing and Speech Rehabilitation,2026,24(03):334-336. DOI： 10.3969/j.issn.1672-4933.2026.03.024.

摘要

耳鸣是临床常见症状，对患者的生活质量造成严重影响。膳食补充剂广泛用于全球健康人群和各类疾病患者，在临床上，耳鸣患者膳食补充剂的使用受到业界关注。本文归纳整理了膳食补充剂与耳鸣相关的临床文献，分析了维生素、矿物质、黄酮、抗氧化剂组合辅助治疗耳鸣的剂量、安全性和有效性，为耳鸣患者安全、合理地使用膳食补充剂提供参考。目前研究对膳食补充剂在耳鸣发生、发展和治疗的影响方面证据不统一。因此，在临床实践中，对于耳鸣患者无需常规做出膳食补充剂的推荐。今后，可进一步研究有效的膳食补充剂与耳鸣的关系。

Abstract

Tinnitus is a common clinical symptom that seriously affects patients 'quality of life. Dietary supplements are widely used in healthy people and patients with various diseases around the world. Clinically

patients with tinnitus are very concerned about the use of dietary supplements. This article summarizes the clinical literature related to dietary supplements and tinnitus

analyzes the dose

safety and effectiveness of vitamins

minerals

flavonoids

and antioxidants in the auxiliary treatment of tinnitus

and provides reference for patients with tinnitus to safely and rationally use dietary supplements. The study has found that current studies provide inconsistent evidence on the impact of the above dietary supplements on the occurrence

development and treatment of tinnitus. Therefore

in clinical practice

there is no need to routinely recommend dietary supplements for patients with tinnitus. In the future

further research can be carried out on the relationship between dietary supplements that may be effective and tinnitus.

关键词

Keywords

references

Tunkel DE , Bauer CA , Sun GH , et al . Clinical practice guideline: tinnitus [J ] . Otolaryngol Head Neck Surg , 2014 , 151 ( 2 Suppl ): S1 - S40 .

刘蓬 , 郑芸 , 卢兢哲 , 等 . «欧洲多学科耳鸣指南:诊断、评估和治疗»解读 [J ] . 听力学及言语疾病杂志 , 2020 , 28 ( 6 ): 727 - 732 .

Gu H , Kong W , Yin H , et al . Prevalence of sleep impairment in patients with tinnitus: a systematic review and single-arm meta-analysis [J ] . Eur Arch Otorhinolaryngol , 2022 , 279 ( 5 ): 2211 - 2221 .

Salazar JW , Meisel K , Smith ER , et al . Depression in Patients with Tinnitus: A Systematic Review [J ] . Otolaryngol Head Neck Surg , 2019 , 161 ( 1 ): 28 - 35 .

余力生 , 杨仕明 , 王秋菊 , 等 . 耳鸣的诊断与治疗 [J ] . 临床耳鼻咽喉头颈外科杂志 , 2022 , 36 ( 5 ): 325 - 334 .

Langguth B , De Ridder D , Schlee W , et al . Tinnitus: Clinical Insights in Its Pathophysiology-A Perspective [J ] . Journal of the Association for Research in Otolaryngology : JARO , 2024 , 25 ( 3 ): 249 - 258 .

Noce A , Romani A , Bernini R . Dietary Intake and Chronic Disease Prevention [J ] . Nutrients , 2021 , 13 ( 4 ): 1358 .

Bhatt JM , Lin HW , Bhattacharyya N . Prevalence, Severity, Exposures, and Treatment Patterns of Tinnitus in the United States [J ] . JAMA otolaryngology-- head neck surgery , 2016 , 142 ( 10 ): 959 - 965 .

Piekara A , Krzywonos M , Kopacz M . Dietary Supplements Intended for Children--Proposed Classification of Products Available on the Market [J ] . Journal of dietary supplements , 2022 , 19 ( 4 ): 431 - 442 .

Nocini R , Henry BM , Mattiuzzi C , et al . Serum Vitamin D Concentration Is Lower in Patients with Tinnitus: A Meta-Analysis of Observational Studies [J ] . Diagnostics (Basel, Switzerland) , 2023 , 13 ( 6 ): 1037 - 1047 .

Aliyeva A , Han JS , Kim Y , et al . Vitamin D Deficiency as a Risk Factor of Tinnitus: An Epidemiological Study [J ] . The Annals of otology, rhinology, and laryngology , 2024 , 133 ( 7 ): 647 - 653 .

Nowaczewska M , Osiński S , Marzec M , et al . The role of vitamin D in subjective tinnitus-A case-control study [J ] . PloS one , 2021 , 16 ( 8 ): e0255482 .

Singh C , Kawatra R , Gupta J , et al . Therapeutic role of Vitamin B12 in patients of chronic tinnitus: A pilot study [J ] . Noise health , 2016 , 18 ( 81 ): 93 - 97 .

Dawes P , Cruickshanks KJ , Marsden A , et al . Relationship Between Diet, Tinnitus, and Hearing Difficulties [J ] . Ear and hearing , 2020 , 41 ( 2 ): 289 - 299 .

Dadgarnia M , Mandegari M , Zand V , et al . The effect of vitamin B12 on idiopathic tinnitus [J ] . American journal of otolaryngology , 2024 , 45 ( 1 ): 104028 .

Narayanan SS , Murali M , Lucas JC , et al . Micronutrients in tinnitus: A National Health and Nutrition Examination Survey analysis [J ] . American journal of otolaryngology , 2022 , 43 ( 3 ): 103460 .

Person OC , Puga ME , Da Silva EM , et al . Zinc supplementation for tinnitus [J ] . The Cochrane database of systematic reviews , 2016 , 11 ( 11 ): CD009832 .

Jun HJ , Ok S , Tyler R , et al . Is Hypozincemia Related to Tinnitus?: A Population Study Using Data From the Korea National Health and Nutrition Examination Survey [J ] . Clinical and experimental otorhinolaryngology , 2015 , 8 ( 4 ): 335 - 338 .

Tang D , Shekhawat GS , Burlutsky G , et al . The Association between Dietary Intakes of Vitamins and Minerals with Tinnitus [J ] . Nutrients , 2024 , 16 ( 15 ): 2535 - 2543 .

Yeh CW , Tseng LH , Yang CH , et al . Effects of oral zinc supplementation on patients with noise-induced hearing loss associated tinnitus: A clinical trial [J ] . Biomedical journal , 2019 , 42 ( 1 ): 46 - 52 .

Atila NE , Atila A , Kaya Z , et al . The Role of Manganese, Cadmium, Chromium and Selenium on Subjective Tinnitus [J ] . Biological trace element research , 2021 , 199 ( 8 ): 2844 - 2850 .

Rojas-Roncancio E , Tyler R , Jun HJ , et al . Manganese and Lipoflavonoid Plus(®) to Treat Tinnitus: A Randomized Controlled Trial [J ] . Journal of the American Academy of Audiology , 2016 , 27 ( 8 ): 661 - 668 .

Tang D , Tran Y , Lewis JR , et al . Associations between intake of dietary flavonoids and the 10-year incidence of tinnitus in older adults [J ] . European journal of nutrition , 2022 , 61 ( 4 ): 1957 - 1964 .

Pawlak-Osińska K , Kaźmierczak H , Marzec M , et al . Assessment of the State of the Natural Antioxidant Barrier of a Body in Patients Complaining about the Presence of Tinnitus [J ] . Oxidative medicine and cellular longevity , 2018 , 2018 : 1439575 .

Celik M , Koyuncu İ . A Comprehensive Study of Oxidative Stress in Tinnitus Patients [J ] . Indian journal of otolaryngology and head and neck surgery , 2018 , 70 ( 4 ): 521 - 526 .

Chauhan B , Arya S , Chauhan K . Ginkgo biloba Administered Singly and Combined With Antioxidants in Tinnitus Patients [J ] . Journal of audiology otology , 2023 , 27 ( 1 ): 37 - 44 .

Petridou AI , Zagora ET , Petridis P , et al . The Effect of Antioxidant Supplementation in Patients with Tinnitus and Normal Hearing or Hearing Loss: A Randomized, Double-Blind, Placebo Controlled Trial [J ] . Nutrients , 2019 , 11 ( 12 ): 3037 - 3060 .

Polanski JF , Soares AD , De Mendon A Cruz OL . Antioxidant therapy in the elderly with tinnitus [J ] . Brazilian journal of otorhinolaryngology , 2016 , 82 ( 3 ): 269 - 274 .

Savastano M , Brescia G , Marioni G . Antioxidant therapy in idiopathic tinnitus: preliminary outcomes [J ] . Archives of medical research , 2007 , 38 ( 4 ): 456 - 459 .

Coelho C , Tyler R , Ji H , et al . Survey on the Effectiveness of Dietary Supplements to Treat Tinnitus [J ] . American journal of audiology , 2016 , 25 ( 3 ): 184 - 205 .

浏览量

下载量

CSCD

文章被引用时，请邮件提醒。

提交

工具集

关联资源

听障儿童声母构音研究进展

老年人工耳蜗植入者认知功能研究进展

耳鸣评估检测方法：从临床实践到多模态整合

耳鸣长期声治疗康复标志物探究

耳鸣量表的评估方法与临床应用